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Tuesday, November 13 • 9:45am - 10:10am
Small Molecules Part 1: Screening Strategies for Today's Tough Targets: Maximizing Diversity in Chemical Matter

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Today's tough targets require new screening technologies to identify novel chemical matter, a blend of functional and structural approaches to interrogate targets in orthogonal assays, and a diverse collection of chemical matter. Traditionally, small molecules of ~ 500 MW and large molecules eg antibodies of ~ 150000 MW have been the focus of drug discovery and development. The need for middle molecules spanning this MW range and with appropriate drug properties is a challenge and opportunity. In this talk, screening strategies, technologies and follow-up assays will be discussed as they are applied to examples of tough targets.

Speaker
avatar for Maria Webb

Maria Webb

Executive Director, Merck
Dr. Webb has extensive experience in large and small pharma with tenure at Bristol Myers Squibb, Pharmacopeia, Ligand Pharmaceuticals, Venenum Biodesign, and Merck over 30 years. She obtained her PhD in Physiology from The Pennsylvania State University, and did post-doctoral research... Read More →


Tuesday November 13, 2018 9:45am - 10:10am
Omni Parker House Omni Parker House, Boston, MA 02108, USA
  • Location Press Room